What Caliber for 16-foot Python?

12 gauge, apparently:

16-foot python found in Florida had eaten a deer

Officials in the Florida Everglades have captured and killed a 16-foot-long Burmese python that had just eaten an adult deer.

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Hardin said the python had recently consumed a 76-pound female deer that had died. He said it was an important capture to help stop the spread of pythons further north.

The python was killed with a shotgun blast.

Wow.